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    CG8564 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38825, updated on 10-May-2024

    Summary

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    Official Symbol
    CG8564provided by FlyBase
    Primary source
    FLYBASE:FBgn0035776
    Locus tag
    Dmel_CG8564
    See related
    AllianceGenome:FB:FBgn0035776
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG8564
    Summary
    Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    Location:
    65F10-65F10; 3-20 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (7385648..7387914, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (7378748..7381014, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Sphingomyelin synthase related Neighboring gene smallminded Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Widespread adaptive evolution of Drosophila genes with sex-biased expression. Pröschel M, et al. Genetics, 2006 Oct. PMID 16951084, Free PMC Article
    2. Wake-up-call, a lin-52 paralogue, and Always early, a lin-9 homologue physically interact, but have opposing functions in regulating testis-specific gene expression. Doggett K, et al. Dev Biol, 2011 Jul 15. PMID 21570388, Free PMC Article
    3. Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes. Hosono C, et al. Nat Cell Biol, 2015 Dec. PMID 26551273
    4. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
    5. Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Schnorrer F, et al. Nature, 2010 Mar 11. PMID 20220848

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables metallocarboxypeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metallocarboxypeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG8564-PA
    CG8564-PC
    NP_001261514.1
    NP_648115.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      7385648..7387914 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001274585.1 → NP_001261514.1  uncharacterized protein Dmel_CG8564, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261514.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0AMU4, M9PEV1
      Conserved Domains (1) summary
      cd03860
      Location:54 → 377
      M14_CP_A-B_like; Peptidase M14 carboxypeptidase subfamily A/B-like

    2. NM_139858.4 → NP_648115.1  uncharacterized protein Dmel_CG8564, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648115.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0AMU4, Q9VS63
      Related
      FBpp0076579
      Conserved Domains (1) summary
      cd03860
      Location:38 → 361
      M14_CP_A-B_like; Peptidase M14 carboxypeptidase subfamily A/B-like
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PEV1 M9PEV1
    Q9VS63 Q9VS63

    Gene LinkOut

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