Cognitive enhancement in schizophrenia: pharmacological and cognitive remediation approaches

Psychiatr Clin North Am. 2012 Sep;35(3):683-98. doi: 10.1016/j.psc.2012.06.008. Epub 2012 Jul 15.

Abstract

This article discusses the measurement of cognition in schizophrenia, its role as a determinant of disability, and treatment efforts to date, including pharmacological and behavioral interventions as well as effective treatments that lead to improved outcomes. The measurement of functioning when patients with schizophrenia receive treatment in the office is addressed. The review focuses on new developments in the creation and adoption of a consensus method for the assessment of cognitive functioning in treatment studies, on the increased appreciation for assessment of functional skills in the prediction of everyday outcomes, and on developments in the basic neuroscience of cognition.

Publication types

  • Review

MeSH terms

  • Behavior Therapy / methods*
  • Cognition Disorders / etiology
  • Cognition Disorders / therapy*
  • Humans
  • Nootropic Agents / therapeutic use*
  • Schizophrenia / complications
  • Schizophrenia / therapy*
  • Treatment Outcome

Substances

  • Nootropic Agents