Ion pair driven self-assembly of a flexible bis-zwitterion in polar solution: formation of discrete nanometer-sized cyclic dimers

Carsten Schmuck; Thomas Rehm; Franziska Gröhn; Katja Klein; Frank Reinhold

doi:10.1021/ja056465c

Ion pair driven self-assembly of a flexible bis-zwitterion in polar solution: formation of discrete nanometer-sized cyclic dimers

J Am Chem Soc. 2006 Feb 8;128(5):1430-1. doi: 10.1021/ja056465c.

Authors

Carsten Schmuck¹, Thomas Rehm, Franziska Gröhn, Katja Klein, Frank Reinhold

Affiliation

¹ University of Würzburg, Institute of Organic Chemistry, Am Hubland, 97074 Würzburg, Germany. schmuck@chemie.uni-wuerzburg.de

PMID: 16448096
DOI: 10.1021/ja056465c

Abstract

The self-complementary flexible bis-zwitterion 1 forms discrete nanometer-sized cyclic dimers via ion pair driven self-assembly even in polar solvents. The existence of such dimers was confirmed by DOSY NMR, FAB-MS, and scattering experiments (DLS, SANS) which all indicate the concentration-dependent formation of cyclic dimers with a hydrodynamic radius of rH approximately 2.5 nm in solution.